Producto del catálogo Hycult Biotech. Referencia del fabricante: HK503.
The liver constitutively produces Lipopolysaccharide (LPS) Binding Protein (LBP), a type 1 acute phase protein that swiftly increases during acute phase responses. LBP assumes a pivotal role in responding to LPS by catalyzing LPS monomerization and facilitating its transfer to (s)CD14 and lipoproteins. This dual function positions LBP at the heart of LPS’s activation pathway—triggering monocyte activation and the subsequent release of inflammatory mediators—and its neutralization pathway—enabling the lipoprotein-mediated uptake and clearance of LPS. Researchers widely use assays to measure functional LBP levels in cell culture supernatants, plasma, and serum from various species, noting its presence escalates in the plasma of healthy individuals during acute phase responses. This highlights LBP’s significance in both activating immune responses to pathogens and mitigating their potentially harmful effects, underscoring its critical role in immunology research.
Watch our demonstration video to see how to use Hycult Biotech LBP ELISA kits with confidence. In this step-by-step guide, our specialists walk you through the complete procedure, helping you achieve accurate, reliable, and consistent results every time.
- Reactividad / especie: N/A
- Aplicaciones: The LBP ELISA kit for a wide variety of species is to be used for the in vitro quantitative determination of LBP in cell culture supernatants, plasma or serum.
Solicítenos una cotización indicando el código. Ficha técnica completa disponible en el fabricante.