Producto del catálogo AbboMax. Referencia del fabricante: 604-030.
"Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene."
- Especificidad: This antibody recognizes human Acetyl-CoA Carboxylase (ACC) protein. The other species are not tested.
- Inmunógeno / antígeno: A synthetic peptide derived from C-terminus of Acetyl-CoA Carbvoxylase 1 protein.
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