Producto del catálogo Hycult Biotech. Referencia del fabricante: HK367.
Complement factor B (CFB), a key enzyme in innate immunity’s complement system, safeguards against microbial threats and has emerged as a crucial biomarker in clinical settings. Vital for the alternative complement pathway’s activation, CFB’s regulation is critical, particularly for protecting against encapsulated bacterial infections. Clinically, its deficiency links to increased susceptibility to infections such as; pneumococcal and meningococcal infections . Moreover, CFB’s diagnostic potential in pancreatic cancer is noteworthy; when combined with CA19-9 in the ComB-CAN panel, it significantly enhances early detection accuracy. Additionally, CFB may contribute to tumor growth by activating the PI3K-AKT pathway, making it an important focus for cancer screening and research.
- Reactividad / especie: Human
- Aplicaciones: The Human Factor B ELISA kit is to be used for the in vitro quantitative determination of Factor B in plasma and serum samples. This kit is intended for laboratory research use only and is not for use in diagnostic or therapeutic procedures.
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